methyl 3-hydroxy-4,5-dimethylthiophene-2-carboxylate

methyl 3-hydroxy-4,5-dimethylthiophene-2-carboxylate - Names and Identifiers

Name	methyl 3-hydroxy-4,5-dimethylthiophene-2-carboxylate
Synonyms	LogP METHYL 3-HYDROXY-4,5-DIMETHYLTHIOPHENE-2-CARBOXYLATE methyl 3-hydroxy-4,5-dimethylthiophene-2-carboxylate 2-Thiophenecarboxylic acid, 3-hydroxy-4,5-dimethyl-, methyl ester
CAS	32822-84-7
InChI	InChI=1/C8H10O3S/c1-4-5(2)12-7(6(4)9)8(10)11-3/h9H,1-3H3

methyl 3-hydroxy-4,5-dimethylthiophene-2-carboxylate - Physico-chemical Properties

Molecular Formula	C8H10O3S
Molar Mass	186.23
Density	1.260±0.06 g/cm3(Predicted)
Melting Point	52-54 °C
Boling Point	278.1±35.0 °C(Predicted)
Flash Point	122°C
Vapor Presure	0.00258mmHg at 25°C
pKa	9.93±0.20(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.562

methyl 3-hydroxy-4,5-dimethylthiophene-2-carboxylate - Introduction

methyl 3-hydroxy-4, is an organic compound with the chemical formula C9H11O3S. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: colorless liquid
-Melting point:-28 ℃
-Boiling point: 196-198 ℃
-Density: 1.20g/cm³
-Solubility: Soluble in ether and ethanol, slightly soluble in water

Use:
methyl 3-hydroxy-4 is often used as an intermediate in organic synthesis and is used to prepare other organic compounds. It also has certain applications in the field of medicine and pesticides.

Method:
methyl 3-hydroxy-4, the preparation method of methyl 3-hydroxy-4 can be realized by the following steps:
(1) 4,5-dimethylthiophene and tetramethyl ammonium carbonate are reacted as raw materials to obtain 4,5-dimethylthiophene -2-carboxylic acid ammonium salt.
(2) An ammonium salt of 4,5-dimethylthiophene-2-carboxylic acid is reacted with hydrogen iodide to obtain 3-hydroxy-4, 5-dimethylthiophene-2-carboxylic acid.
(3) Finally, 3-hydroxy-4, 5-dimethylthiophene-2-carboxylic acid is reacted with methanol to obtain methyl 3-hydroxy-4, pyridine.

Safety Information:
methyl 3-hydroxy-4, should be treated as an organic compound, need to pay attention to some safety matters:
-Avoid contact with skin, eyes and respiratory system. In the case of accidental contact, rinse immediately with plenty of water and seek medical help.
-Avoid contact with oxidizing agents, strong acids or strong bases during storage to prevent dangerous reactions.
-Pay attention to well-ventilated laboratory conditions during use, and wear personal protective equipment, such as laboratory gloves, protective glasses and protective masks.
-Detailed safety operation information should be referred to the relevant chemical safety information before use.

Last Update：2024-04-09 21:00:56